diff --git a/BUILD.gn b/BUILD.gn
index 8a6f96dba..a731844e1 100644
--- a/BUILD.gn
+++ b/BUILD.gn
@@ -176,6 +176,9 @@ static_library("libyuv_internal") {
       "-ffp-contract=fast",  # Enable fma vectorization for NEON.
     ]
   }
+  if (!libyuv_use_mmi) {
+    defines += [ "LIBYUV_DISABLE_MMI" ]
+  }
 }
 
 if (libyuv_use_neon) {