diff --git a/BUILD.gn b/BUILD.gn
index 30ebafb3d..4a2dbf182 100644
--- a/BUILD.gn
+++ b/BUILD.gn
@@ -198,9 +198,7 @@ static_library("libyuv_internal") {
     deps += [ "//third_party:jpeg_includes" ]
   }
 
-  # Always enable optimization for Release and NaCl builds (to workaround
-  # crbug.com/538243).
-  if (!is_debug || is_nacl) {
+  if (!is_debug) {
     configs -= [ "//build/config/compiler:default_optimization" ]
 
     # Enable optimize for speed (-O2) over size (-Os).